Dr. Sheena Josselyn
From: SickKids news
Scientists use a peptide to strengthen connections between brain cells and restore memory in a pre-clinical model.
Research led at The Hospital for Sick Children (SickKids) is illuminating the mechanism underlying memory, which could result in future therapeutic targets for conditions such as Alzheimer’s disease and dementia.
Alzheimer’s disease is a condition that causes memory loss, characterized by the accumulation of a protein, called A-beta, in the brain that damages neurons and their connections.
Published in Nature Neuroscience, Drs. Paul Frankland and Sheena Josselyn, Senior Scientists in the Neurosciences & Mental Health program, used a peptide to block adverse effects of the accumulation of A-beta in pre-clinical models – a technique that showed promise in restoring memory.
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